Alpha-1 Therapy

Alpha-1 refers to a genetic condition known as alpha-1 antitrypsin deficiency (AATD). It is an inherited disorder that affects the production and function of a protein called alpha-1 antitrypsin (AAT) in the body. AAT is primarily produced by the liver and plays a crucial role in protecting the lungs from damage caused by enzymes released by certain white blood cells.

Alpha-1 therapy from a home infusion pharmacy typically involves the use of augmentation therapy. Augmentation therapy is the main treatment for individuals with alpha-1 antitrypsin deficiency. It involves infusing purified alpha-1 antitrypsin protein derived from human plasma into the bloodstream to supplement the deficient or dysfunctional protein.

How Do You Know if You Need Therapy for Alpha-1?

Not everyone diagnosed with alpha-1 antitrypsin deficiency (AATD) requires treatment. The need for treatment depends on several factors, including the severity of the deficiency, the presence of symptoms or complications, and the progression of lung or liver disease.

Some individuals with alpha-1 antitrypsin deficiency may have normal lung function and remain asymptomatic throughout their lives. In such cases, close monitoring and lifestyle modifications, such as avoiding smoking and occupational exposures that can damage the lungs, may be recommended.

However, individuals with alpha-1 antitrypsin deficiency who develop symptoms or show signs of lung or liver disease may benefit from specific treatments.

Your healthcare provider will decide if your diagnoses requires treatment.

How Often do Patients Receive Alpha-1 Therapy?

The frequency of Alpha-1 Therapy, also known as augmentation therapy, can vary depending on the specific treatment regimen prescribed by the healthcare provider. In general, augmentation therapy is typically administered on a regular basis to maintain stable levels of Alpha-1 Antitrypsin (AAT) protein in the blood.

The most common frequency for Alpha-1 Therapy is once a week or every two weeks, with regular infusions of the purified AAT protein. The exact dosing schedule may vary depending on the specific product used and the individual’s response to treatment. The infusion duration can also vary, ranging from 15 minutes to a few hours, depending on the specific protocol and the patient’s needs.

How is Alpha-1 Therapy (Augmentation) Administered?

Alpha-1 therapy, also known as augmentation therapy, is administered through intravenous infusion. Your home infusion pharmacy’s nurse will administer the infusion. The infusion can last from 15 minutes to a few hours, depending on the product used and recommended infusion rate.

Alpha-1 therapy is typically repeated at regular intervals as prescribed by the healthcare provider. The frequency of infusions can vary, but it is commonly administered on a weekly or biweekly basis.

It’s important for patients to receive Alpha-1 Therapy under the guidance of a healthcare professional experienced in the administration of intravenous therapies. They can ensure the proper administration technique, monitor for any adverse reactions, and provide necessary support throughout the infusion process.

Are there Side Effects from Alpha-1 Therapy?

Alpha-1 therapy, also known as augmentation therapy, is generally considered safe and well-tolerated. However, like any therapy, there can be potential side effects. Alpha-1 Therapy side effects can include:

  1. Infusion Site Reactions
  2. Mild Flu-Like Symptoms
  3. Allergic Reactions

It’s important for patients to report any side effects they experience to their healthcare provider promptly. The healthcare provider can evaluate the symptoms, provide appropriate guidance, and determine if any adjustments to the treatment plan are necessary.

Do I need a Prescription for Alpha-1 Therapy?

If you have been diagnosed and think it may be time for Alpha-1 Therapy, or if you are curious to learn more about it, we recommend speaking with your healthcare provider. You will need a prescription from your healthcare provider to start Alpha-1 Therapy. Our team can assist you with administration, teaching, follow-up and more.

Is Anti-Infective Therapy Covered by Insurance?

As part of the Vital Care network of home infusion pharmacies, we are an in-network provider with most all insurance carriers and are able to work with your insurance company to provide your infusion services at the lowest out-of-pocket cost for you.

When you work with us, you get the local care you deserve with the strength of a national company. Our dedicated insurance team will work with your insurance company saving you time and hassle. Call the pharmacy at 402-462-2929 or email to see how we can help you get better with our accredited home infusion services.